IT1t dihydrochloride

Catalog # Availability Size / Price Qty
4596/10
4596/50
Cat.No. 4596 - IT1t dihydrochloride | C21H34N4S2.2HCl | CAS No. 1092776-63-0
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Description: Potent CXCR4 antagonist

Chemical Name: N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride

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Biological Activity

Potent CXCR4 antagonist (IC50 = 1.1 nM in calcium mobilization assays). Orally available. Blocks interaction with the HIV envelope protein, gp120 (IC50 = 7 nM, inhibition of X4-tropic HIV-1IIIB attachment).

Technical Data

Formula:
C21H34N4S2.2HCl
Solubility:
Soluble to 10 mM in DMSO and to 100 mM in water
Storage:
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
CAS No:
1092776-63-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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