JMV 449

Catalog # Availability Size / Price Qty
1998/1
JMV 449
1 Image
Description: Potent neurotensin receptor agonist
Product Details
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Biological Activity

Potent, metabolically stable neurotensin receptor agonist peptide (IC50 = 0.15 nM for inhibition of [125I]-NT binding to neonatal mouse brain; EC50 = 1.9 nM for contraction of guinea pig ileum). Produces long-lasting hypothermic, neuroprotective and analgesic effects in mice following central administration in vivo.

Technical Data

M.Wt:
746.96
Formula:
C38H66N8O7
Sequence:
KKPYIL

(Modifications: Lys-1 - Lys-2 peptide bond replace with Ψ(CH2-NH))

Solubility:
Soluble to 0.80 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
139026-66-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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