JTE 907

Tocris Bioscience | Catalog # 2479

Selective CB2 receptor inverse agonist
Tocris Bioscience

Key Product Details

Description

Selective CB2 receptor inverse agonist
View all Cannabinoid R2 / CB2 Inverse Agonists »

Product Description

JTE 907 is a highly selective cannabinoid CB2 receptor inverse agonist. Binds with high affinity to rat, mouse and human CB2 receptors (Ki values are 0.38, 1.55 and 35.9 nM respectively). Produces anti-inflammatory effects in vivo.

Product Specifications for JTE 907

Molecular Weight

438.48

Formula

C24H26N2O6

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

N-(1,3-Benzodioxol-5-ylmethyl)-1,2-dihydro-7-methoxy-2-oxo-8-(pentyloxy)-3-quinolinecarboxamide

CAS Number

282089-49-0

PubChem ID

9867770

InChI Key

GRAJFFFXJYFVOC-UHFFFAOYSA-N

SMILES

CCCCCOC1=C2NC(=O)C(=CC2=CC=C1OC)C(=O)NCC1=CC2=C(OCO2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 43.85 100
Ethanol 4.38 10

Preparing Stock Solutions for JTE 907

The following data is based on the product molecular weight 438.48.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.28 mL 11.40 mL 22.81 mL
5 mM 0.46 mL 2.28 mL 4.56 mL
10 mM 0.23 mL 1.14 mL 2.28 mL
50 mM 0.05 mL 0.23 mL 0.46 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 36 publications citing the usage of this product.

Product Documents for JTE 907

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for JTE 907

For research use only

Customer Reviews for JTE 907 (1)

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  • JTE 907 suppress skin inflammation
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Verified Customer | Posted 02/04/2020
    Dissolved in DMSO
    Orally administered JTE-907 (10 mg/kg) in a murine allergic contact dermatitis model.
    JTE 907 2479

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