Highly selective cannabinoid CB2
receptor inverse agonist. Binds with high affinity to rat, mouse and human CB2
values are 0.38, 1.55 and 35.9 nM respectively). Produces anti-inflammatory effects in vivo
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In vitro and in vivo pharmacological characterization of JTE-907, a novel selective ligand for cannabinoid CB2 receptor.
Iwamura et al.
Involvement of cannabinoid CB2 receptor-mediated response and efficacy of cannabinoid CB2 receptor inverse agonist, JTE 907, in cutaneous inflammation in mice.
Ueda et al.
The cannabinoid CB2 receptor inverse agonist JTE-907 suppresses spontaneous itch-associated responses of NC mice, a model of atopic dermatitis.
Maekawa et al.
The citations listed below are publications that use Tocris products. Selected citations for JTE 907 include:
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