JW 480
Chemical Name: 2-Isopropylphenyl(2-(naphthalen-2-yl)ethyl)carbamate
Purity: ≥98%
Biological Activity
Potent and selective inhibitor of the serine hydrolase enzyme KIAA1363 (AADACL1) (IC50 = 20 nM in mouse brain). Impairs migration, invasion, survival and tumor growth of prostate cancer cell lines in vivo. Reduces monoalkylglycerol ether (MAGE) levels.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis.
Chang et al.
Chem.Biol., 2011;18:476
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