Catalog Number: 4327
Chemical Name: 2-Isopropylphenyl(2-(naphthalen-2-yl)ethyl)carbamate
Biological Activity
Potent and selective inhibitor of the serine hydrolase enzyme KIAA1363 (AADACL1) (IC50 = 20 nM in mouse brain). Impairs migration, invasion, survival and tumor growth of prostate cancer cell lines in vivo. Reduces monoalkylglycerol ether (MAGE) levels.
Technical Data
  • M.Wt:
    333.42
  • Formula:
    C22H23NO2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Storage:
    Store at -20°C
  • CAS No:
    1354359-53-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license from The Scripps Research Institute.
Background References
  1. A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis.
    Chang et al.
    Chem.Biol., 2011;18:476

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