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Potent and selective poly (ADP ribose) glycohydrolase (PARG) inhibitor; cell permeable
O-GlcNAcase and β-hexosaminidase inhibitor
High affinity inhibitor of KDO 8-P synthase; also DDAH1 inhibitor
Selective allosteric glutaminase (GLS1) inhibitor
α/β-hydrolase domain 6 (ABHD6) inhibitor; antiepileptic
Potent O-GlcNAcase inhibitor
Inhibits tetrahydrobiopterin synthesis and thus NOS activity
Ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor
Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1)
Selective PFKFB3 inhibitor
Selective and reversible lysophospholipase 2 (LYPLA2) inhibitor
Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor
Allosteric inhibitor of glutaminase
Selective inhibitor of LTA4 hydrolase
Potent and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor
Potent soluble epoxide hydrolase inhibitor; orally bioavailable and brain penetrant
HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant
