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JX 401

2657 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2657/10
2657/50
JX 401 | CAS No. 349087-34-9 | p38 Inhibitors
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Description: Potent, reversible p38α inhibitor

Chemical Name: 1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine

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Biological Activity

Potent, reversible inhibitor of p38α that displays no activity on the p38γ isoform (IC50 values are 32 nM and > 10 μM respectively). Inhibits the differentiation of myoblasts to myotubes in mammalian cells in culture.

Technical Data

Formula:
C21H25NO2S
Solubility:
Soluble to 75 mM in DMSO and to 50 mM in ethanol
Storage:
Store the unopened product at room temperature. Do not use past expiration date.
CAS No:
349087-34-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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