Potent and irreversible α
-hydrolase domain 6 (ABHD6) inhibitor (IC50
= 44 nM). Exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors.
Patel et al.