Kaempferol

  ( 1 citations )    
Product Datasheet
Catalog Number:3603
Alternate Names:Kempferol
Chemical Name:3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Product Details
Citations (1)
Reviews
Biological Activity
Naturally occurring flavonoid found in Gingko biloba and red wines that activates the mitochondrial Ca2+ uniporter (EC50 = 7 μM). Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.
Technical Data
  • M.Wt:
    286.24
  • Formula:
    C15H10O6
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    520-18-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Kaempferol include:

1 Citations: Showing 1 - 1

  1. Identification of small molecules that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death.
    Authors: Tran Et al.
    ACS Chem Biol  2014;9:2796

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