Recombinant Human KCNMB3 His Protein

Novus Biologicals | Catalog # NBP2-51813

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
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Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 82-207 of Human KCNMB3

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSKPFMLSI QREESTCTAI HTDIMDDWLD CAFTCGVHCH GQGKYPCLQV FVNLSHPGQK ALLHYNEEAV QINPKCFYTP KCHQDRNDLL NSALDIKEFF DHKNGTPFSC FYSPASQSED VILIKKYDQ

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

16.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human KCNMB3 His Protein

SDS-PAGE: Recombinant Human KCNMB3 His Protein [NBP2-51813]

SDS-PAGE: Recombinant Human KCNMB3 His Protein [NBP2-51813]

SDS-Page: KCNMB3 Recombinant Protein [NBP2-51813] - 15% SDS Page (3 ug)

Formulation, Preparation, and Storage

NBP2-51813
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KCNMB3

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for this gene.

Alternate Names

BK channel subunit beta-3, BKBETA3, Hbeta3, KCNMB2, KCNMBL, potassium large conductance calcium-activated channel, subfamily M beta member3, slo-beta-3, subfamily M subunit beta-3, voltage and Ca2+ activated potassium channel Maxi K beta 3subunit

Gene Symbol

KCNMB3

Additional KCNMB3 Products

Product Documents for Recombinant Human KCNMB3 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human KCNMB3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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