Ketanserin tartrate

  ( 14 citations )    
Product Datasheet
Catalog Number:0908
Alternate Names:R 41 468
Chemical Name:3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione tartrate
Product Details
Citations (14)
Supplemental Products
Reviews
Biological Activity
Selective 5-HT2A serotonin receptor antagonist; can also be used to discriminate between 5-HT1D and 5-HT1B receptor subtypes.
Technical Data
  • M.Wt:
    545.52
  • Formula:
    C22H22FN3O3.C4H6O6
  • Solubility:
    Soluble to 10 mM in water
  • Purity:
    >97
  • Storage:
    Store at RT
  • CAS No:
    83846-83-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Ketanserin tartrate include:

14 Citations: Showing 1 - 10
Filter your results:

  1. Monoaminergic modulation of GABAergic transmission onto cerebellar globular cells.
    Authors: Hirono
    Neuropharmacology  2017;118:79
  2. Potentiation of 5-methoxy-N,N-dimethyltryptamine-induced hyperthermia by harmaline and the involvement of activation of 5-HT1A and 5-HT2A receptors.
    Authors: Jiang Et al.
    Br J Pharmacol  2015;89:342
  3. Serotonin-2C receptor agonists decrease potassium-stimulated GABA release in the nucleus accumbens.
    Authors: Kasper Et al.
    Neuropharmacology  2015;69:78
  4. Behavioral and neurochemical changes in mesostriatal dopaminergic regions of the rat after chronic administration of the cannabinoid receptor agonist WIN55,212-2.
    Authors: Fanarioti Et al.
    Synapse  2015;18
  5. Cerebral markers of the serotonergic system in rat models of obesity and after Roux-en-Y gastric bypass.
    Authors: Ratner Et al.
    Neuron  2012;20:2133
  6. Gene therapy by targeted adenovirus-mediated knockdown of pulmonary endothelial Tph1 attenuates hypoxia-induced pulmonary hypertension.
    Authors: Morecroft Et al.
    Cereb Cortex  2012;20:1516
  7. Serotonin, via HTR2 receptors, excites neurons in a cortical-like premotor nucleus necessary for song learning and production.
    Authors: Wood Et al.
    J Neurosci  2011;31:13808
  8. Serotonin receptor activity is necessary for olfactory learning and memory in Drosophila melanogaster.
    Authors: Johnson Et al.
    Neuroscience  2011;192:372
  9. Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuation.
    Authors: Kleinbongard Et al.
    Circ Res  2011;108:344
  10. In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension.
    Authors: Morecroft Et al.
    Int J Neuropsychopharmacol  2010;85:593
  11. Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses.
    Authors: Watakabe Et al.
    Br J Pharmacol  2009;19:1915
  12. Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior.
    Authors: González-Maeso Et al.
    Mol Ther  2007;53:439
  13. Serotonergic and nonserotonergic dorsal raphe neurons are pharmacologically and electrophysiologically heterogeneous.
    Authors: Marinelli Et al.
    J Neurophysiol  2004;92:3532
  14. 5-hydroxytryptamine receptors mediating contraction in human small muscular pulmonary arteries: importance of the 5-HT1B receptor.
    Authors: Morecroft Et al.
    Obesity (Silver Spring)  1999;128:730
Expand to show all Citations

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used Ketanserin tartrate?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee