Ketoconazole

Catalog # Availability Size / Price Qty
1103/100

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Ketoconazole | CAS No. 65277-42-1 | Cytochrome P450 Inhibitors
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Description: Cytochrome P450c17 inhibitor

Chemical Name: cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl] methoxy]phenyl]piperazine

Purity: ≥99%

Product Details
Citations (4)
Reviews

Biological Activity

Ketoconazole is an inhibitor of cytochrome P450c17. Enhances the formation of myelin basic protein-positive oligodendrocytes from oligodendrocyte progenitor cells in vitro and promotes remyelination in vivo. Also an antifungal agent. Brain penetrant.

Technical Data

M.Wt:
531.44
Formula:
C26H28Cl2N4O4
Solubility:
Soluble to 50 mM in ethanol and to 75 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
65277-42-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Ketoconazole

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