Antifungal agent; potent inhibitor of cytochrome P450c17.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Kishimoto T et al.
Leucocyte Typing VI. Garland Publishing Inc. London.
Inhibition of human adrenal steroidogenic enzymes in vitro by imidazole drugs including ketoconazole.
Ayub and Levell
J.Steroid Biochem., 1989;32:515
Blockade of HERG and Kv1.5 by ketoconazole.
Dumaine et al.
Ketoconazole inhibition of the bifunctional cytochrome P450c17 does not affect androgen formation from the endogenous lyase substrate.
Kuhn-Velten et al.