KI-7

Key Product Details

Product Description

KI-7 is an adenosine A_2B receptor positive allosteric modulator. Potentiates the NECA (Cat. No. 1691) -induced increase in cAMP production in CHO cells expressing A_2B receptors. Also potentiates the effects of NECA and the A_2B receptor agonist BAY 60-6583 (Cat. No. 4472) in mediating osteoblast differentiation from MSCs in vitro.

Product Specifications for KI-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for KI-7

The following data is based on the product molecular weight 354.40.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	5.64 mL	28.22 mL	56.43 mL
2.5 mM	1.13 mL	5.64 mL	11.29 mL
5 mM	0.56 mL	2.82 mL	5.64 mL
25 mM	0.11 mL	0.56 mL	1.13 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Trincavelli Allosteric modulators of human A_2B adenosine receptor. Biochim.Biophys.Acta 2014 PMID: 24361612
• Trincavelli Osteoblast differentiation and survival: A role for A_2B adenosine receptor allosteric modulators. Biochim.Biophys.Acta 2014 PMID: 25241343

Product Documents for KI-7