High affinity adenosine receptor agonist (Ki
values are 6.2, 14, and 20 nM for human A3
receptors respectively; EC50
= 2.4 μ
M for human A2B
). Inhibits platelet aggregation and is centrally active in vivo
Soluble to 40 mM in DMSO
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
5'-N-ethylcarboxamidoadenosine: a potent inhibitor of human platelet aggregation.
Cusack and Hourani
Adenosine receptors and their ligands.
Naunyn Schmiedebergs Arch.Pharmacol., 2000;362:382
Adenosine agonists CGS21680 and NECA inhibit the initiation of cocaine self-administration.
Knapp et al.
The citations listed below are publications that use Tocris products. Selected citations for NECA include:
Showing Results 1 - 10 of 13