KISS1 305

Tocris Bioscience | Catalog # 7490

Kisspeptin1 receptor agonist
Tocris Bioscience
Discontinued Product
7490 has been discontinued. View all KiSS1R/GPR54 products.

Key Product Details

Description

Kisspeptin1 receptor agonist

Product Description

KISS1 305 is a potent Kisspeptin1 receptor agonist (EC50 = 10 nM). It binds with high affinity to rat and human KISS1 receptors with Ki values of 0.14 nM and 0.11 nM respectively. In vivo, chronic administration of KISS1 305 reduces plasma testosterone and genital organ weights in male rats.

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the KISS1-305 probe summary on the SGC website.

External Portal Information

Chemicalprobes.org

is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of KISS1-305 is reviewed on the chemical probes website.

Product Specifications for KISS1 305

Molecular Weight

1165.32

Formula

C56H76N16O12

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

872717-97-0

InChI Key

YSVWFFNZZGLLAI-XNTOLAJGSA-N

SMILES

O=C(N[C@@H](CCCNC(NC)=N)C(N[C@@H](CC1=CC=CC=C1)C(N)=O)=O)[C@H](CC(C)C)NC(NNC([C@H](CC2=CC=CC=C2)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](NC([C@@H](CC3=CC=C(C=C3)O)N)=O)CC4=CC=NC=C4)=O)=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solubility Soluble to 1mg/ml in water

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Product Documents for KISS1 305

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for KISS1 305

For research use only

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