Catalog Number: 4130
Chemical Name: 2-[N-(4'-Methoxybenzenesulfonyl)]amino-N-(4'-chlorophenyl)-2-propenyl-N-methylbenzylamine phosphate
Biological Activity
Inactive analog of the CaM kinase II inhibitor KN 93 (Cat. No. 1278). Potassium channel (Kv1.2, 1.4, 1.5, 2.1, 3.2 and hERG) blocker in vitro.
Technical Data
  • M.Wt:
    554.98
  • Formula:
    C24H25ClN2O3S.H3PO4
  • Solubility:
    Soluble to 10 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    1135280-28-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. KN-93 (2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine), a calcium/calmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated
    Rezazadeh et al.
    J.Pharmacol.Exp.Ther., 2005;317:292
Citations:

The citations listed below are publications that use Tocris products. Selected citations for KN 92 include:

1 Citations: Showing 1 - 1

  1. Acute simvastatin inhibits K ATP channels of porcine coronary artery myocytes.
    Authors: Seto Et al.
    Oncotarget 2013;8:e66404

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