Selective adenosine A1
receptor antagonist; displays 890-fold selectivity for rat A1
receptors over A2A
values are 0.19 and 170 nM respectively). Displays no effect on recombinant rat A3
receptors expressed on CHO cells at concentrations up to 10 μ
M. Exhibits diuretic and renal protective effects in rats.
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All Tocris products are intended for laboratory research use only.
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