Kynurenic acid sodium salt

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3694/100
iGluR Antagonists Small Molecule
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Description: Sodium salt of kynurenic acid (Cat. No. 0223)

Chemical Name: 4-Hydroxyquinoline-2-carboxylic acid sodium salt

Purity: ≥99%

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Biological Activity

Sodium salt of kynurenic acid (Cat. No. 0223), a broad spectrum EAA antagonist.

Technical Data

M.Wt:
211.15
Formula:
C10H6NNaO3
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
2439-02-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35.
    Wang J, Simonavicius N, Wu X et al.
    J Biol Chem.
  2. An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid.
    Perkins and Stone
    Brain Res., 1982;247:184
  3. The 'kynurenate test', a biochemical assay for putative cognition enhancers.
    Pittaluga et al.
    J.Pharmacol.Exp.Ther., 1997;283:82
  4. NMDA receptors and ligands in the vertebrate CNS.
    Stone and Burton
    Progr.Neurobiol., 1988;30:333

Product Datasheets

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