Kynurenic acid sodium salt

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Kynurenic acid sodium salt | CAS No. 2439-02-3 | iGluR Antagonists
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Description: Sodium salt of kynurenic acid (Cat. No. 0223)

Chemical Name: 4-Hydroxyquinoline-2-carboxylic acid sodium salt

Purity: ≥99%

Product Details
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Biological Activity

Kynurenic acid sodium salt is a sodium salt of kynurenic acid (Cat. No. 0223), a broad spectrum EAA antagonist.

Technical Data

Soluble to 100 mM in water and to 50 mM in DMSO
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35.
    Wang J, Simonavicius N, Wu X et al.
    J Biol Chem.
  2. An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid.
    Perkins and Stone
    Brain Res., 1982;247:184
  3. The 'kynurenate test', a biochemical assay for putative cognition enhancers.
    Pittaluga et al.
    J.Pharmacol.Exp.Ther., 1997;283:82
  4. NMDA receptors and ligands in the vertebrate CNS.
    Stone and Burton
    Progr.Neurobiol., 1988;30:333

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