Kynurenic acid

Tocris Bioscience | Catalog # 0223

Broad spectrum glutamatergic antagonist
Tocris Bioscience

Key Product Details

Description

Broad spectrum glutamatergic antagonist
View all iGluR Antagonists »

Product Description

Kynurenic acid is a broad spectrum EAA antagonist. Putative GPR35 ligand. Kynurenic acid protects tissues in cardiac, cerebral, renal, and retinal ischemia models via activation of GPR35 and induction of ATP synthase dimerization in an ATPIF1-dependent and pertussis toxin (Cat. No. 3097) sensitive manner.

Sodium Salt also available.

Product Specifications for Kynurenic acid

Molecular Weight

189.17

Formula

C10H7NO3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

4-Hydroxyquinoline-2-carboxylic acid

CAS Number

492-27-3

PubChem ID

3845

InChI Key

HCZHHEIFKROPDY-UHFFFAOYSA-N

SMILES

OC(=O)C1=CC(O)=C2C=CC=CC2=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 9.46 50
1eq. NaOH 18.92 100

Preparing Stock Solutions for Kynurenic acid

The following data is based on the product molecular weight 189.17.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.29 mL 26.43 mL 52.86 mL
5 mM 1.06 mL 5.29 mL 10.57 mL
10 mM 0.53 mL 2.64 mL 5.29 mL
50 mM 0.11 mL 0.53 mL 1.06 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 201 publications citing the usage of this product.

Product Documents for Kynurenic acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Kynurenic acid

For research use only

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