A potent D2
dopamine receptor selective antagonist, with affinities of 2.4, 100 and 220 nM for D2
receptors respectively. Centrally active following systemic administration in vivo
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Antagonism of the effects of (+)-PD 128907 on midbrain dopamine neurones in rat brain slices by a selective D2 receptor antagonist L-741,626.
Bowery et al.
S33084, a novel, potent, selective, and competitive antagonist at dopamine D3-receptors: II. Functional and behavioral profile compared with GR218,231 and L741,626.
Millan et al.
Human D2 and D4 dopamine receptors couple through βγ G-protein subunits to inwardly rectifying K+ channels (GIRK1) in a Xenopus oocyte expression system: selective antagonism by L-741,626 and L-745,870 r
Pillai et al.
3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.
Kulagowski et al.
The citations listed below are publications that use Tocris products. Selected citations for L-741,626 include:
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