L-741,742 hydrochloride

  ( 2 citations )    
Product Datasheet
Catalog Number:1004
Chemical Name:5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole hydrochloride
Product Details
Citations (2)
Reviews
Biological Activity
A potent and highly selective D4 dopamine receptor antagonist, with Ki values of > 1700, 770 and 3.5 nM at cloned human D2, D3 and D4 receptors.
Technical Data
  • M.Wt:
    417.38
  • Formula:
    C23H25N2ClO.HCl
  • Solubility:
    Soluble to 10 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    874882-93-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Merck Sharp and Dohme Ltd.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for L-741,742 hydrochloride include:

2 Citations: Showing 1 - 2
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  1. Norepinephrine activates dopamine D4 receptors in the rat lateral habenula.
    Authors: Root Et al.
    J Neurosci  2015;35:3460
  2. Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation.
    Authors: Bastianetto Et al.
    BMC Neurosci  2006;7:28

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