L-NIO dihydrochloride
Tocris Bioscience | Catalog # 0546
Product Description
L-NIO dihydrochloride is an Inhibitor of nitric oxide (NO) synthase. Inhibits iNOS, eNOS and nNOS. Active in vivo.
Product Specifications for L-NIO dihydrochloride
Molecular Weight
Formula
Storage
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 24.61 | 100 |
Preparing Stock Solutions for L-NIO dihydrochloride
The following data is based on the product molecular weight 246.13.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.06 mL | 20.31 mL | 40.63 mL |
| 5 mM | 0.81 mL | 4.06 mL | 8.13 mL |
| 10 mM | 0.41 mL | 2.03 mL | 4.06 mL |
| 50 mM | 0.08 mL | 0.41 mL | 0.81 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 20 publications citing the usage of this product.
- Mulligan Protective effects of inhibitors of nitric oxide synthase in immune complex-induced vasculitis. Br.J.Pharmacol. 1992 PMID: 1281719
- Rees Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br.J.Pharmacol. 1990 PMID: 1706208
- Moncada XIV. International Union of Pharmacology nomenclature in nitric oxide research. Pharmacol.Rev. 1997 PMID: 9228663
Product Documents for L-NIO dihydrochloride
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for L-NIO dihydrochloride
For research use only
Related Research Areas
Citations for L-NIO dihydrochloride
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