L-NIO dihydrochloride

  ( 7 citations )    
Product Datasheet
Catalog Number:0546
Chemical Name:N5-(1-Iminoethyl)-L-ornithine dihydrochloride
Product Details
Citations (7)
Biological Activity
Inhibitor of nitric oxide (NO) synthase. Inhibits iNOS, eNOS and nNOS. Active in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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The citations listed below are publications that use Tocris products. Selected citations for L-NIO dihydrochloride include:

7 Citations: Showing 1 - 7
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  1. Relaxin peptide hormones are protective during the early stages of ischemic stroke in male rats.
    Authors: Bergeron Et al.
    PLoS Negl Trop Dis  2015;156:638
  2. Neuronal and Endothelial Nitric Oxide Synthases in the Paraventricular Nucleus Modulate Sympathetic Overdrive in Insulin-Resistant Rats.
    Authors: Lu Et al.
    Endocrinology  2015;10:e0140762
  3. Neuronal nitric oxide synthase-dependent elevation in adiponectin in the rostral ventrolateral medulla underlies g protein-coupled receptor 18-mediated hypotension in conscious rats.
    Authors: Penumarti and Abdel-Rahman
    J Pharmacol Exp Ther  2014;351:44
  4. Vasorelaxin: a novel arterial smooth muscle-relaxing eicosapeptide from the skin secretion of the Chinese piebald odorous frog (Odorrana schmackeri).
    Authors: Wu Et al.
    PLoS One  2013;8:e55739
  5. Roles of endothelial nitric oxide synthase (eNOS) and mitochondrial permeability transition pore (MPTP) in epoxyeicosatrienoic acid (EET)-induced cardioprotection against infarction in intact rat hearts.
    Authors: Gross Et al.
    J Mol Cell Cardiol  2013;59:20
  6. Lactate dilates cochlear capillaries via type V fibrocyte-vessel coupling signaled by nNOS.
    Authors: Dai Et al.
    Am J Physiol Heart Circ Physiol  2011;301:H1248
  7. Differential central NOS-NO signaling underlies clonidine exacerbation of ethanol-evoked behavioral impairment.
    Authors: Bender and Abdel-Rahman
    Alcohol Clin Exp Res  2010;34:555


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