Chemical Name: NG-Monomethyl-L-arginine acetate
Biological ActivityL-NMMA acetate is a competitive, irreversible inhibitor of all three NOS isoforms.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Inactivation of macrophage nitric oxide synthase activity by N(G)-methyl-L-arginine.
Olken et al.
Characterisation of three inhibitors of endothelial nitric oxide synthase in vivo and in vitro.
Rees et al.
N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a differential pattern of inactivation toward the three nitric oxide synthases.
Reif and McCreedy et al.
Identification of arginine as a precursor of endothelium-derived relaxing factor.
Saksuma et al.
Citations for L-NMMA acetate
The citations listed below are publications that use Tocris products. Selected citations for L-NMMA acetate include:
6 Citations: Showing 1 - 6
STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection.
Authors: Queval Et al.
Sci Rep 2016;6:29297
Uremic Toxins Induce ET-1 Release by Human Proximal Tubule Cells, which Regulates Organic Cation Uptake Time-Dependently.
Authors: Schophuizen Et al.
J Neurosci 2015;4:234
Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity.
Authors: Echeverría Et al.
PLoS One 2014;9:e94146
An anxiolytic-like effect of hyperbaric oxygen in the mouse light/dark exploration test.
Authors: Carlile Et al.
Life Sci 2012;90:267
Modulation of inhibitory activity by nitric oxide in the thalamus.
J Neurophysiol 2007;97:3386
beta-OE, dehydroepiandrosterone, and dehydroepiandrosterone sulfate protect against N-MthD.-aspartate-induced neurotoxicity in rat hippocampal neurons by different mechanisms.
Authors: Kurata Et al.
J Pharmacol Exp Ther 2004;311:237
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