Competitive, irreversible inhibitor of all three NOS isoforms.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a differential pattern of inactivation toward the three nitric oxide synthases.
Reif and McCreedy et al.
Identification of arginine as a precursor of endothelium-derived relaxing factor.
Saksuma et al.
Inactivation of macrophage nitric oxide synthase activity by N(G)-methyl-L-arginine.
Olken et al.
Characterisation of three inhibitors of endothelial nitric oxide synthase in vivo and in vitro.
Rees et al.
The citations listed below are publications that use Tocris products. Selected citations for L-NMMA acetate include:
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