Chemical Name: 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine isethionate
Biological ActivityLamotrigine isethionate is a water-soluble salt of lamotrigine (Cat. No. 1611). Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.
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Lamotrigine reduces voltage-gated sodium currents in rat central neurons in culture.
Zona and Avoli
Cardioprotective effect of lamotr. after focal ischemia in rats.
Smith and Meldrum
Modulation of calcium and potassium currents by lamotr.
Grunze et al.
Neurochemical and behavioral aspects of lamotr.
Leach et al.
Citation for Lamotrigine isethionate
The citations listed below are publications that use Tocris products. Selected citations for Lamotrigine isethionate include:
1 Citation: Showing 1 - 1
Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K+ Channel THIK-1.
Authors: Madry Et al.
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