Langerin/CD207 Antibody (817G7) - Azide and BSA Free

Novus Biologicals | Catalog # DDX0377P-100

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Flow Cytometry, Functional, Inhibition Activity

Cited:

In-Cell Western (ICW)

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 817G7

Format

Azide and BSA Free
View all Langerin/CD207 Primary Antibodies »

Product Specifications

Immunogen

human Langerin-transfected eukaryotic cells

Epitope

Recognizes the CRD domain of the langerin molecule.

Reactivity Notes

Human

Specificity

human Langerin (extracellular epitope)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Langerin/CD207 Antibody (817G7) - Azide and BSA Free

Flow Cytometry: Langerin/CD207 Antibody (817G7) [DDX0377P-100]
Flow Cytometry: Langerin/CD207 Antibody (817G7) [DDX0377P-100]

Applications for Langerin/CD207 Antibody (817G7) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:1000
Application Notes
Use in Inhibition Activity reported in scientific literature (PMID:33905459) This monoclonal antibody may be used between 5-20 ug/ml. Blocks HIV-gp120

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

Tris-NaCl (pH 8.0)

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Langerin/CD207

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Alternate Names

CD207

Gene Symbol

CD207

Additional Langerin/CD207 Products

Product Documents for Langerin/CD207 Antibody (817G7) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for Langerin/CD207 Antibody (817G7) - Azide and BSA Free

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Langerin/CD207 Antibody (817G7) - Azide and BSA Free

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FAQs

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Associated Pathways

Dendritic Cell Lineage Development Pathways Dendritic Cell Lineage Development Pathway Thumbnail