Catalog Number: 4422
Biological Activity
N-terminally acylated analog of LF 11 (Cat. No. 4421). Displays enhanced antibacterial and LPS-binding activities.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Phe-1 = CH3-(CH2)10-CO-NH-Phe, Arg-11 = C-terminal amide)

  • Solubility:
    Soluble to 2 mg/ml in 30% acetonitrile / water
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Influence of N-acylation of a peptide derived from human lactoferricin on membrane selectivity.
    Zweytick et al.
    Biochim.Biophys.Acta, 2006;1758:1426
  2. Effect of the hydrophobicity to net positive charge ratio on antibacterial and anti-endotoxin activities of structurally similar antimicrobial peptides.
    Rosenfeld et al.
    Biochemistry, 2010;49:853
  3. Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide.
    Andra et al.
    Biochem.J., 2005;385:135
Tocris Peptides
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LF 11

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