Lauryl-LF 11

Name: Lauryl-LF 11
Brand: Tocris Bioscience
SKU: 4422

Tocris Bioscience | Catalog # 4422

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Product Documents

Analog of LF 11 (Cat. No. 4421); antibiotic

Discontinued Product

4422 has been discontinued. View all Antibiotics products.

Technical Data
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Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Analog of LF 11 (Cat. No. 4421); antibiotic

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Product Description

Lauryl-LF 11 is a N-terminally acylated analog of LF 11 (Cat. No. 4421). Displays enhanced antibacterial and LPS-binding activities.

Product Specifications for Lauryl-LF 11

Molecular Weight

1712.11

Formula

C₈₁H₁₃₄N₂₆O₁₅

Storage

Store at -20°C

CAS Number

832729-14-3

PubChem ID

90488941

InChI Key

AUHGQKBFMDAWAQ-BSHYLFJSSA-N

SMILES

CCCCCCCCCCCNC(CC1CCCCC1)C(O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)CN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 2mg/ml in 30% acetonitrile / water

Calculators

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Background References

References are publications that support the biological activity of the product.

Rosenfeld Effect of the hydrophobicity to net positive charge ratio on antibacterial and anti-endotoxin activities of structurally similar antimicrobial peptides. Biochemistry 2010 PMID: 20058937
Andra Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 2005 PMID: 15344905
Zweytick Influence of N-acylation of a peptide derived from human lactoferricin on membrane selectivity. Biochim.Biophys.Acta 2006 PMID: 16616888

Product Documents for Lauryl-LF 11

Certificate of Analysis

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Product Specific Notices for Lauryl-LF 11

For research use only

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