Catalog Number: 4421
Biological Activity
Peptide based on the lipopolysaccharide (LPS)-binding region of human lactoferricin. Neutralizes LPS; displays antimicrobial activity against Gram-negative and Gram-positive bacteria. Analog lauryl-LF 11 (Cat. No. 4422) available.
Technical Data
  • M.Wt:
    1529.81
  • Formula:
    C69H112N26O14
  • Sequence:
    FQWQRNIRKVR

    (Modifications: Arg-11 = C-terminal amide)

  • Solubility:
    Soluble to 2 mg/ml in 20% acetonitrile / water
  • Storage:
    Store at -20°C
  • CAS No:
    832729-13-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide.
    Andra et al.
    Biochem.J., 2005;385:135
  2. Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides.
    Sanchez-Gomez et al.
    BMC Mirobiol., 2008;11:196
  3. Structural origin of endotoxin neutralization and antimicrobial activity of a lactoferrin-based peptide.
    Japelj et al.
    J.Biol.Chem., 2005;280:16955
Tocris Peptides
Description Application Cat# Citations Images  

Lauryl-LF 11

4422  
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