Catalog Number: 2959
Chemical Name: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester hydrochloride
Biological Activity
L-type Ca2+ channel blocker that displays higher vascular selectivity than felodipine (Cat. No. 2960). Causes peripheral vasodilation with only weak negative inotropic activity. Antihypertensive.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in ethanol
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Lercanidipine. A review of its efficacy in the management of hypertension.
    Bang et al.
    Drugs, 2003;63:2449
  2. Molecular mechanisms of vasoselectivity of the 1,4-dihydropyridine lercanidipine.
    Wirtz and Herzig
    Br.J.Pharmacol., 2004;142:275
  3. Antihypertensive effects of lercanidipine in experimental hypertensive rats and dogs.
    Sironi et al.
    Arzneim.Forsch., 1996;46:152

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