Leukotriene B4

Catalog # Availability Size / Price Qty
Leukotriene B4 | CAS No. 71160-24-2 | Leukotriene and Related Receptor Agonists
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Description: BLT1/BLT2 receptor agonist and potent chemotactic factor
Alternative Names: LTB4, 5,12-DiHETE

Chemical Name: (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-6,8,10,14-eicosatetraenoic acid

Purity: ≥97%

Product Details
Citations (1)
Supplemental Products

Biological Activity

Leukotriene B4 is a potent lipid inflammatory mediator derived from the 5-lipoxygenase pathway of arachidonic acid metabolism. Binds to BLT1 and BLT2 receptors and acts as a potent chemotactic agent and activator of leukocytes. Also displays antiviral activity towards DNA viruses and retroviruses.

Technical Data

Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 50?g/ml)
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Leukotriene B4: an inflammatory mediator in vivo.
    Bray et al.
    Prostaglandins, 1981;22:213
  2. Leukotriene B4 in inflammation.
    Crit.Rev.Immunol., 1990;10:1
  3. Leukotriene B4: metabolism and signal transduction.
    Yokomitso et al.
    Arch.Biochem.Biophys., 2001;385:231

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Citation for Leukotriene B4

The citations listed below are publications that use Tocris products. Selected citations for Leukotriene B4 include:

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