Chemical Name: (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-6,8,10,14-eicosatetraenoic acid
Biological ActivityLeukotriene B4 is a potent lipid inflammatory mediator derived from the 5-lipoxygenase pathway of arachidonic acid metabolism. Binds to BLT1 and BLT2 receptors and acts as a potent chemotactic agent and activator of leukocytes. Also displays antiviral activity towards DNA viruses and retroviruses.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Leukotriene B4: an inflammatory mediator in vivo.
Bray et al.
Leukotriene B4 in inflammation.
Leukotriene B4: metabolism and signal transduction.
Yokomitso et al.
Citation for Leukotriene B4
The citations listed below are publications that use Tocris products. Selected citations for Leukotriene B4 include:
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