Lidocaine

Catalog # Availability Size / Price Qty
3057/50
3057/10
Lidocaine | CAS No. 137-58-6 | Voltage-gated Sodium Channel Blockers
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Description: Na+ channel blocker

Chemical Name: 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide

Purity: ≥99%

Product Details
Citations (2)
Reviews (1)

Biological Activity

Anasthetic and class Ib antiarrhythmic agent. Blocks voltage-gated sodium channels in the inactivated state.

Technical Data

M.Wt:
234.34
Formula:
C14H22N2O
Solubility:
Soluble to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
137-58-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for Lidocaine

The citations listed below are publications that use Tocris products. Selected citations for Lidocaine include:

2 Citations: Showing 1 - 2

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Lidocaine in prelimbic medial prefrontal cortex blocks cue-induced reinstatement of MDMA seeking
By Kevin Ball on 01/25/2019
Species: Rat

Bilateral microinjections of lidocaine (100 micrograms/0.5 microliter/side) into prelimbic, but not infralimbic, medial prefrontal cortex blocked cue-induced reinstatement of MDMA (ecstasy)-seeking behavior compared with saline microinjections into the same region. Lidocaine microinjections into either region did not, however, have an effect on food-maintained responding, ruling out a nonspecific disruption of motor performance.

PMID: 4078904 Reference

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