Lidocaine

Tocris Bioscience | Catalog # 3057

Na+ channel blocker
Tocris Bioscience

Key Product Details

Description

Na+ channel blocker
View all Voltage-gated Sodium Channel Blockers »

Product Description

Lidocaine is an anasthetic and class Ib antiarrhythmic agent. Blocks voltage-gated sodium channels in the inactivated state.

Product Specifications for Lidocaine

Molecular Weight

234.34

Formula

C14H22N2O

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2-Diethylamino-N-(2,6-dimethylphenyl)acetamide

CAS Number

137-58-6

PubChem ID

3676

InChI Key

NNJVILVZKWQKPM-UHFFFAOYSA-N

SMILES

O=C(CN(CC)CC)NC1=C(C)C=CC=C1C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 23.43 100
Ethanol 23.43 100

Preparing Stock Solutions for Lidocaine

The following data is based on the product molecular weight 234.34.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.27 mL 21.34 mL 42.67 mL
5 mM 0.85 mL 4.27 mL 8.53 mL
10 mM 0.43 mL 2.13 mL 4.27 mL
50 mM 0.09 mL 0.43 mL 0.85 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 47 publications citing the usage of this product.

Product Documents for Lidocaine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Lidocaine

For research use only

Related Research Areas

Ion Channels and Regulators

Customer Reviews for Lidocaine (1)

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  • Lidocaine in prelimbic medial prefrontal cortex blocks cue-induced reinstatement of MDMA seeking
    Name: Kevin Ball
    Species: Rat
    Assay Type: In Vivo
    Verified Customer | Posted 01/25/2019
    Bilateral microinjections of lidocaine (100 micrograms/0.5 microliter/side) into prelimbic, but not infralimbic, medial prefrontal cortex blocked cue-induced reinstatement of MDMA (ecstasy)-seeking behavior compared with saline microinjections into the same region. Lidocaine microinjections into either region did not, however, have an effect on food-maintained responding, ruling out a nonspecific disruption of motor performance.
    Lidocaine 3057

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