Lisuride maleate

Catalog # Availability Size / Price Qty
4052/10
4052/50
Lisuride maleate | CAS No. 19875-60-6 | Non-selective Dopamine Receptor Agonists
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Description: Dopamine agonist; antiparkinson's agent

Chemical Name: N'-[(8α)-9,10-Didehydro-6-methylergolin-8-yl]-N,N-diethylurea maleate

Purity: ≥99%

Product Details
Citations (2)
Supplemental Products
Reviews

Biological Activity

Dopamine receptor agonist and anti-Parkinson's agent. Displays high affinity for D2, D3 and D4 receptors along with 5-HT1A. Exhibits some 5-HT2B receptor antagonist properties. Decreases prolactin release; reduces inflammatory mediators such as TNF-α and IL6. Exhibits anticonvulsive effects. Acts similar to bromocriptine (Cat. No. 0427).

Technical Data

M.Wt:
454.52
Formula:
C20H26N4O.C4H4O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
19875-60-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Lisuride, a DA receptor agonist with 5-HT2B receptor antagonist properties: absence of cardiac valvulopathy adverse drug reaction reports supports the concept of a crucial role for 5-HT2B receptor agonism in cardiac valvular fibrosis
    Hofmann et al.
    Clin.Neuropharmacol., 2006;29:80
  2. Anticonvulsive effects of the DA agonist lisuride maleate after experimental traumatic brain injury.
    Zweckberger et al.
    Neurosci.Lett., 2010;470:150
  3. Transdermal lisuride delivery in the treatment of Parkinson's disease.
    Woitalla et al.
    J.Neural Transm., 2004;68:89

Product Datasheets

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Citations for Lisuride maleate

The citations listed below are publications that use Tocris products. Selected citations for Lisuride maleate include:

2 Citations: Showing 1 - 2

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