Chemical Name: N'-[(8α)-9,10-Didehydro-6-methylergolin-8-yl]-N,N-diethylurea maleate
Biological ActivityDopamine receptor agonist and anti-Parkinson's agent. Displays high affinity for D2, D3 and D4 receptors along with 5-HT1A. Exhibits some 5-HT2B receptor antagonist properties. Decreases prolactin release; reduces inflammatory mediators such as TNF-α and IL6. Exhibits anticonvulsive effects. Acts similar to bromocriptine (Cat. No. 0427).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Lisuride, a DA receptor agonist with 5-HT2B receptor antagonist properties: absence of cardiac valvulopathy adverse drug reaction reports supports the concept of a crucial role for 5-HT2B receptor agonism in cardiac valvular fibrosis
Hofmann et al.
Anticonvulsive effects of the DA agonist lisuride maleate after experimental traumatic brain injury.
Zweckberger et al.
Transdermal lisuride delivery in the treatment of Parkinson's disease.
Woitalla et al.
J.Neural Transm., 2004;68:89
Citations for Lisuride maleate
The citations listed below are publications that use Tocris products. Selected citations for Lisuride maleate include:
2 Citations: Showing 1 - 2
Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy.
Authors: Chan Et al.
Structural determinants of 5-HT2B receptor activation and biased agonism.
Authors: McCorvy Et al.
Nat Struct Mol Biol 2018;25:787
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