LNT 1

Catalog # Availability Size / Price Qty
6510/5
LNT 1 | CAS No. 824983-91-7 | Hydrolase Inhibitors
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Description: Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response

Chemical Name: 1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-3-hydroxythieno[3,2-d]pyrimidine-2,4(1H,3H)-dione

Purity: ≥98%

Product Details
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Biological Activity

Potent flap endonuclease 1 (FEN1) inhibitor (IC50 = 46.4 nM for hFEN1-336Δ). Cytotoxic to SW620 colorectal cancer cells in vitro; induces DNA damage response.

Technical Data

M.Wt:
332.33
Formula:
C15H12N2O5S
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
824983-91-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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