LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C, also called NGL-2 (netrin-G ligand-2), NGL-3 and NGL-1, respectively, are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. Mature LRRC4 family members are type I transmembrane proteins with an extracellular region that contains nine LRRs, a C2-type Ig-like domain, and a Thr-rich segment. LRRC4 family members share ~55% aa identity, but each recognizes different ligands. LRRC4 and LRRC4C recognize Netrin-G2 and Netrin-G3, respectively, while LRRC4B recognizes the receptor tyrosine phosphatases LAR/PTPRF, PTPR delta and PTPR sigma.
LRRC4 Antibody - BSA Free
Novus Biologicals | Catalog # NBP3-13186
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Key Product Details
Species Reactivity
Validated:
Mouse, Rat
Predicted:
Human (98%), Rhesus Macaque (98%). Backed by our 100% Guarantee.
Applications
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
BSA Free
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Product Specifications
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of mouse LRRC4. The exact sequence is proprietary.
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Description
Centrifuge briefly prior to opening.
Scientific Data Images for LRRC4 Antibody - BSA Free
Western Blot: LRRC4 Antibody [NBP3-13186]
Western Blot: LRRC4 Antibody [NBP3-13186] - Various tissue extracts (75 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with LRRC4 antibody (NBP3-13186) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Applications for LRRC4 Antibody - BSA Free
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS, 20% Glycerol
Format
BSA Free
Preservative
0.025% Proclin 300
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: LRRC4
Long Name
Leucine-rich Repeat Containing 4
Alternate Names
BAG, NAG14
Gene Symbol
LRRC4
Additional LRRC4 Products
Product Documents for LRRC4 Antibody - BSA Free
Certificate of Analysis
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Product Specific Notices for LRRC4 Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
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