LRRK2 [p Ser935] Antibody (SR1453) - BSA Free

Novus Biologicals | Catalog # NBP3-21519

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Mouse

Applications

Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1453 expressed in HEK293

Format

BSA Free
View all LRRK2 Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human phospho-LRRK2 [Ser935] (Uniprot #: Q5S007)

Modification

p Ser 935

Specificity

Detects endogenous levels of total phospho-LRRK2 [Ser935]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

286 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit LRRK2 [p Ser935] Antibody (SR1453) - BSA Free (NBP3-21519) is a recombinant monoclonal antibody validated for use in WB and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for LRRK2 [p Ser935] Antibody (SR1453) - BSA Free

Western Blot: LRRK2 [p Ser 935] Antibody (SR1453) [NBP3-21519] -

Western Blot: LRRK2 [p Ser 935] Antibody (SR1453) [NBP3-21519] - Western blot analysis using NBP3-21519 in WT-LRRK2 cell lysate treated LRRK2.

Applications for LRRK2 [p Ser935] Antibody (SR1453) - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LRRK2

LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

LRRK2 antibodies are useful tools for neurodegeneration research and certian kinase signaling pathway studies.

Long Name

Leucine-rich Repeat Ser/Thr Protein Kinase 2

Alternate Names

AURA17, Dardarin, PARK8, ROCO2

Gene Symbol

LRRK2

Additional LRRK2 Products

Product Documents for LRRK2 [p Ser935] Antibody (SR1453) - BSA Free

Certificate of Analysis

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Product Specific Notices for LRRK2 [p Ser935] Antibody (SR1453) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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