Selective, competitive antagonist of BLT2
values are ~ 1 and > 10 μ
M at human recombinant BLT2
receptors respectively). Inhibits LTB4
-induced contraction of lung parenchyma (pA2
= 7.2), and reduces LTB4
-mediated airway obstruction in guinea pigs following i.v. and oral administration.�.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Pulmonary actions of LY255283, a leukotriene B4 receptor antagonist.
Silbaugh et al.
Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2.
Yokomizo et al.
Leukotriene B4 receptor antagonists: the LY255283 series of hydroxyacetophenones.
Herron et al.
The citations listed below are publications that use Tocris products. Selected citations for LY 255283 include:
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