receptor antagonist (pKi
= 9.3). More than 100-fold selective over 5-HT2A
. Attenuates amphetamine-induced locomotion in the rat.
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All Tocris products are intended for laboratory research use only.
Potent, selective tetrahydro-β-carboline antagonists of the serotonin 2B (5-HT2B) contractile receptor in the rat stomach fundus.
Audia et al.
The central serotonin2B receptor: a new pharmacological target to modulate the mesoaccumbens dopaminergic pathway activity.
Auclair et al.