LY 303511

Catalog # Availability Size / Price Qty
2418/5
PI 3-Kinase Inhibitors Small Molecule
1 Image
Description: Negative control of LY 294002 (Cat. No. 1130)

Chemical Name: 2-(1-Piperazinyl)-8-phenyl-4H-1-benzopyran-4-one

Purity: ≥99%

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Biological Activity

Negative control compound for LY 294002 PI 3-kinase inhibitory activity. Blocks voltage-gated potassium (Kv) channels (IC50 = 64.6 μM) and inhibits IL-1β-stimulated NF-κB activation, attenuating MCP-1 expression. Antiproliferative. Also inhibits the BET bromodomain proteins BRD2, BRD3 and BRD4.

Active Analog also available.

Technical Data

M.Wt:
306.36
Formula:
C19H18N2O2
Solubility:
Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
154447-38-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

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