LY 341495 disodium salt

Key Product Details

Product Description

LY 341495 disodium salt is a Highly potent and selective group II metabotropic glutamate receptor antagonist. Disodium salt of LY 341495 (Cat. No. 1209).

Product Specifications for LY 341495 disodium salt

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for LY 341495 disodium salt

The following data is based on the product molecular weight 397.33.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.52 mL	12.58 mL	25.17 mL
5 mM	0.50 mL	2.52 mL	5.03 mL
10 mM	0.25 mL	1.26 mL	2.52 mL
50 mM	0.05 mL	0.25 mL	0.50 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.

• Ornstein 2-Substituted (2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl) glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 2. Effects of aromatic substitution, pharmacological characterization, and bioav J.Med.Chem. 1998 PMID: 9464367
• Johnson [³H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells. Neuropharmacology 1999 PMID: 10530814
• Fitzjohn The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity. Neuropharmacology 1998 PMID: 9886667

Product Documents for LY 341495 disodium salt