LY 341495 disodium salt
Chemical Name: (2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl) propanoic acid disodium salt
Biological ActivityHighly potent and selective group II metabotropic glutamate receptor antagonist. Disodium salt of LY 341495 (Cat. No. 1209).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity.
Fitzjohn et al.
[3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells.
Johnson et al.
2-Substituted (2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl) glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 2. Effects of aromatic substitution, pharmacological characterization, and bioav
Ornstein et al.
Citations for LY 341495 disodium salt
The citations listed below are publications that use Tocris products. Selected citations for LY 341495 disodium salt include:
2 Citations: Showing 1 - 2
Neural Mechanisms Mediating Motion Sensitivity in Parasol Ganglion Cells of the Primate Retina.
Authors: Manookin Et al.
Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli.
Authors: Ilatovskaya Et al.
Am J Physiol Cell Physiol 2013;305:C1050
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