Activator of phospholipase C (PLC). Stimulates superoxide generation, Ca2+
release and inositol phosphate formation in a variety of cell types. Also inhibits growth of the leukemic cell lines U937 and THP-1. Inactive control o-3M3FBS
(Cat. No. 1942) available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Identification of a compound that directly stimulates phospholipase C activity.
Bae et al.
Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation.
Krjukova et al.
The novel phospholipase C activator, m-3M3FBS, induces monocytic leukemia cell apoptosis.
Lee et al.
Cancer Lett., 2005;222:227
The citations listed below are publications that use Tocris products. Selected citations for m-3M3FBS include:
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