MDL 11,939

Tocris Bioscience | Catalog # 0870

5-HT2A antagonist
Tocris Bioscience

Key Product Details

Description

5-HT2A antagonist
View all 5-HT2A Receptor Antagonists »

Product Description

MDL 11,939 is an orally active 5-HT2A receptor antagonist; displays selectivity for 5-HT2A receptors over 5-HT2C receptors (Ki values are 0.54, 2.5, 81.6 and ~10,000 nM at rabbit 5-HT2A, human 5-HT2A, rabbit 5-HT2C and human 5-HT2C receptors respectively).

Product Specifications for MDL 11,939

Molecular Weight

295.42

Formula

C20H25NO

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

α-Phenyl-1-(2-phenylethyl)-4-piperidinemethanol

CAS Number

107703-78-6

PubChem ID

71781

InChI Key

AXNGJCOYCMDPQG-UHFFFAOYSA-N

SMILES

OC(C1CCN(CCC2=CC=CC=C2)CC1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 14.77 50
Ethanol 14.77 50

Preparing Stock Solutions for MDL 11,939

The following data is based on the product molecular weight 295.42.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 6.77 mL 33.85 mL 67.70 mL
2.5 mM 1.35 mL 6.77 mL 13.54 mL
5 mM 0.68 mL 3.39 mL 6.77 mL
25 mM 0.14 mL 0.68 mL 1.35 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 39 publications citing the usage of this product.

Product Documents for MDL 11,939

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MDL 11,939

For research use only

Customer Reviews for MDL 11,939 (1)

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  • we used it for in vivo infusions
    Name: noelia weisstaub
    Species: Rat
    Assay Type: In Vivo
    Verified Customer | Posted 01/04/2018
    We used MDL for in vivo infusion at different regions of the brain. It works very well. It is very stable and easy to dissolve and not sticky which make it easy to infuse.

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