Catalog Number: 0640
Chemical Name: Tropanyl 3,5-dichlorobenzoate
Biological Activity
5-HT3 antagonist.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. MDL 72222: a potent and highly selective antagonist at neuronal 5-hydroxytryptamine receptors.
    Naunyn Schmiedebergs Arch.Pharmacol., 1984;326:36
  2. The pharmacology and function of 5-HT3 receptors.
    Richardson and Engel
    Trends Neurosci., 1986;9:424

The citations listed below are publications that use Tocris products. Selected citations for MDL 72222 include:

Showing Results 1 - 2 of 2

  1. Increased serotonin transporter expression reduces fear and recruitment of parvalbumin interneurons of the amygdala.
    Authors: Bocchio Et al.
  2. Neuregulin-1 enhances depolarization-induced GABA release.
    Authors: Woo Et al.
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