MDL 72222

Tocris Bioscience | Catalog # 0640

5-HT3 antagonist
Tocris Bioscience

Key Product Details

Description

5-HT3 antagonist
View all 5-HT3 Receptor Antagonists »

Product Description

MDL 72222 is a 5-HT3 antagonist.

Product Specifications for MDL 72222

Molecular Weight

314.21

Formula

C15H17Cl2NO2

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

Tropanyl 3,5-dichlorobenzoate

CAS Number

40796-97-2

PubChem ID

1683

InChI Key

MNJNPLVXBISNSX-UHFFFAOYSA-N

SMILES

CN1C2CCC1CC(C2)OC(=O)C1=CC(Cl)=CC(Cl)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 100

Preparing Stock Solutions for MDL 72222

The following data is based on the product molecular weight 314.21.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.18 mL 15.91 mL 31.83 mL
5 mM 0.64 mL 3.18 mL 6.37 mL
10 mM 0.32 mL 1.59 mL 3.18 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 41 publications citing the usage of this product.

Product Documents for MDL 72222

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MDL 72222

For research use only

Customer Reviews for MDL 72222 (1)

5 out of 5
1 Customer Rating
5 Stars
100%
4 Stars
0%
3 Stars
0%
2 Stars
0%
1 Stars
0%

Have you used MDL 72222?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Customer Images

Showing  1 - 1 of 1 review Showing All
Filter By:
Clear Filters X
  • Pharmacological block of 5-HT3 receptors
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: Cerebellum
    Verified Customer | Posted 08/31/2019
    MDL 72222 was used for pharmacological isolation of glycine receptors response in nucleated membrane patches pulled from cerebellar granule cells. Clear response was obtained, with characteristic conductance states pertinent to glycine receptor. Picture: recording of single-channel openings of glycine receptor with 10 microM MDL 72222 in perfusion solution.
    MDL 72222 0640

There are no reviews that match your criteria.

Showing  1 - 1 of 1 review Showing All