MDL 72222

Catalog # Availability Size / Price Qty
0640/50
MDL 72222 | CAS No. 40796-97-2 | 5-HT3 Receptor Antagonists
1 Image
Description: 5-HT3 antagonist

Chemical Name: Tropanyl 3,5-dichlorobenzoate

Purity: ≥99%

Product Details
Citations (6)
Supplemental Products
Reviews (1)

Biological Activity

5-HT3 antagonist.

Technical Data

M.Wt:
314.21
Formula:
C15H17Cl2NO2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
40796-97-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. MDL 72222: a potent and highly selective antagonist at neuronal 5-hydroxytryptamine receptors.
    Fozard
    Naunyn Schmiedebergs Arch.Pharmacol., 1984;326:36
  2. The pharmacology and function of 5-HT3 receptors.
    Richardson and Engel
    Trends Neurosci., 1986;9:424

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for MDL 72222

Average Rating: 5 (Based on 1 Review)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used MDL 72222?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Pharmacological block of 5-HT3 receptors
By Anonymous on 08/31/2019
Application: Species: Mouse

MDL 72222 was used for pharmacological isolation of glycine receptors response in nucleated membrane patches pulled from cerebellar granule cells. Clear response was obtained, with characteristic conductance states pertinent to glycine receptor. Picture: recording of single-channel openings of glycine receptor with 10 microM MDL 72222 in perfusion solution.


Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.