Melittin

Name: Melittin
Brand: Tocris Bioscience
SKU: 1193
Price: 211 USD
Availability: InStock

Tocris Bioscience | Catalog # 1193

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Citations (13)

Product Documents

Inhibits Gs and stimulates Gi activity

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Inhibits Gs and stimulates Gi activity

View all G Protein (Heterotrimeric) Inhibitors »

Product Description

Melittin is a inhibits G_s and stimulates G_i activity. Inhibits protein kinase C and cAMP-dependent protein kinases. Na⁺/K⁺ ATPase inhibitor.

Product Specifications for Melittin

Molecular Weight

2847.00

Formula

C₁₃₁H₂₂₉N₃₉O₃₁

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

20449-79-0

PubChem ID

16133648

InChI Key

VDXZNPDIRNWWCW-JFTDCZMZSA-N

SMILES

[H]NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Concentration 1 (C1)

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Concentration 2 (C2)

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 13 publications citing the usage of this product.

Mousli G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides. TiPS 1990 PMID: 2122563
Raynor Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin. J.Biol.Chem. 1991 PMID: 1847132
Fukushima Melittin, a metabostatic peptide inhibiting G_s activity. Peptides 1998 PMID: 9663445

Product Documents for Melittin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Melittin

For research use only

Citations for Melittin

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