Biological ActivityInhibits Gs and stimulates Gi activity. Inhibits protein kinase C and cAMP-dependent protein kinases. Na+/K+ ATPase inhibitor.
(Modifications: Gln-26 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Melittin, a metabostatic peptide inhibiting Gs activity.
Fukushima et al.
G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides.
Mousli et al.
Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin.
Raynor et al.
Citation for Melittin
The citations listed below are publications that use Tocris products. Selected citations for Melittin include:
1 Citation: Showing 1 - 1
β1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons.
Authors: Meitzen Et al.
J Neurochem 2011;116:984
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