Mer Antibody (8H11) - BSA Free

Novus Biologicals | Catalog # NBP3-26145

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG4 (S228P) Clone # 8H11 expressed in HEK293

Format

BSA Free
View all Mer Primary Antibodies »

Product Specifications

Immunogen

Recombinant Human Mer protein [UniProt Q12866]

Clonality

Monoclonal

Host

Human

Isotype

IgG4 (S228P)

Scientific Data Images for Mer Antibody (8H11) - BSA Free

Mer Antibody (8H11)

ELISA: Mer Antibody (8H11) [NBP3-26145] -

ELISA: Mer Antibody (8H11) [NBP3-26145] - The Binding Activity of Mer with anti-Mer Antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mer at 2 ug/mL can bind Mer Antibody, the EC50 is 41.31-72.08 ng/mL.

Applications for Mer Antibody (8H11) - BSA Free

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50% Glycerol, 0.01M PBS, PH 7.4

Format

BSA Free

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: Mer

MerTK (c-mer, Nyk, Eyk) is a tyrosine kinase that belongs to a family of transmembrane receptors (1). MerTk has been implicated in reversible cell growth arrest, survival, proliferation and cell adhesion. Growth arrest specific protein 6 (Gas6) is an activating ligand for MerTK (2-3). MerTK is required for clearance of apoptotic cells by mononuclear phagocytes in mice; with its absence resulting in progressive lupus like autoimmunity (4). Defects in MERTK are a cause of retinitis pigmentosa (RP) (5).

Long Name

Receptor Tyrosine Protein Kinase Mer

Alternate Names

c-Eyk, C-mer, MerTK

Gene Symbol

MERTK

Additional Mer Products

Product Documents for Mer Antibody (8H11) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Mer Antibody (8H11) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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