Catalog Number: 0549
Alternate Names: Methylergonovine maleate
Chemical Name: [8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-6-methylergoline-8-carboxamide maleate
Biological Activity
Active metabolite of methysergide (Cat. No. 1064); uterotonic agent and oxytocic.
Technical Data
  • M.Wt:
    455.51
  • Formula:
    C20H25N3O2.C4H4O4
  • Solubility:
    Soluble to 25 mM in water
  • Purity:
    >98%
  • Storage:
    Desiccate at RT
  • CAS No:
    57432-61-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References

  1. Kishimoto T et al.
    Leucocyte Typing VI. Garland Publishing Inc. London.
  2. Actions of non-peptide ergot alkaloids at 5-HT1-like and 5-HT2 receptors mediating vascular smooth muscle contraction.
    MacLennan and Martin
    Naunyn Schmiedebergs Arch.Pharmacol., 1990;342:120
  3. Methylergometrine, an active metabolite of methysergide.
    Muller-Schweinitzer and Tapparelli
    Cephalalgia, 1986;6:35
  4. 5-Hydroxytryptamine (5-HT) contracts the guinea-pig isolated iliac artery via 5-HT1-like and 5-HT2 receptors.
    Pertz
    Naunyn Schmiedebergs Arch.Pharmacol., 1993;348:558
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Methylergometrine maleate include:

1 Citations: Showing 1 - 1

  1. Ergot Alkaloids (Re)generate New Leads as Antiparasitics.
    Authors: Chan Et al.
    Cell Signal 2015;9:e0004063
Tocris Small Molecules
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Methysergide maleate

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