Methysergide maleate

  ( 7 citations )    
Product Datasheet
Catalog Number:1064
Chemical Name:[8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8-carboxamide maleate
Product Details
Citations (7)
Supplemental Products
Reviews
Biological Activity
Mixed 5-HT1/5-HT2 receptor antagonist.
Technical Data
  • M.Wt:
    469.54
  • Formula:
    C21H27N3O2.C4H4O4
  • Solubility:
    Soluble to 10 mM in water with gentle warming
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    129-49-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Methysergide maleate include:

7 Citations: Showing 1 - 7
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  1. Reduced levels of serotonin 2A receptors underlie resistance of Egr3-deficient mice to locomotor suppression by clozapine.
    Authors: Williams Et al.
    Neuropsychopharmacology  2012;37:2285
  2. Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT2A and mGlu2 receptors in the adult offspring.
    Authors: Moreno Et al.
    Hypertension  2011;31:1863
  3. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
    Authors: Murray Et al.
    J Neurophysiol  2011;106:925
  4. Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors.
    Authors: Murray Et al.
    Nat Med  2010;16:694
  5. Autocrine and paracrine roles for ATP and serotonin in mouse taste buds.
    Authors: Huang Et al.
    Neuron  2009;29:13909
  6. Serotonin modulates olfactory processing in the antennal lobe of Drosophila.
    Authors: Dacks Et al.
    J Neurosci  2009;23:366
  7. Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior.
    Authors: González-Maeso Et al.
    J Neurosci  2007;53:439

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