Chemical Name: [8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8-carboxamide maleate
Biological ActivityMethysergide maleate is a mixed 5-HT1/5-HT2 receptor antagonist.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin).
Hoyer et al.
Citations for Methysergide maleate
The citations listed below are publications that use Tocris products. Selected citations for Methysergide maleate include:
7 Citations: Showing 1 - 7
Reduced levels of serotonin 2A receptors underlie resistance of Egr3-deficient mice to locomotor suppression by cloz.
Authors: Williams Et al.
Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT2A and mGlu2 receptors in the adult offspring.
Authors: Moreno Et al.
Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
Authors: Murray Et al.
J Neurophysiol 2011;106:925
Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors.
Authors: Murray Et al.
Nat Med 2010;16:694
Autocrine and paracrine roles for ATP and serotonin in mouse taste buds.
Authors: Huang Et al.
Serotonin modulates olfactory processing in the antennal lobe of Drosophila.
Authors: Dacks Et al.
J Neurosci 2009;23:366
Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior.
Authors: González-Maeso Et al.
J Neurosci 2007;53:439
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