Chemical Name: 17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium bromide
Biological ActivityPeripherally restricted μ-opioid antagonist. Antagonizes the effects of morphine (Cat. No. 5158) on contraction of isolated guinea pig ileum. Quaternary derivative of naltrexone (Cat. No. 0677).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Quaternary naltrexone: evidence for the central mediation of discriminative stimulus effects of narcotic agonists and antagonists.
Valentino et al.
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