Methylnaltrexone bromide New
Chemical Name: 17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium bromide
Biological ActivityPeripherally restricted μ-opioid antagonist. Antagonizes the effects of morphine (Cat. No. 5158) on contraction of isolated guinea pig ileum. Quaternary derivative of naltrexone (Cat. No. 0677).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Quaternary naltrexone: evidence for the central mediation of discriminative stimulus effects of narcotic agonists and antagonists.
Valentino et al.
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