Metoprolol tartrate

Catalog # Availability Size / Price Qty
Metoprolol tartrate | CAS No. 56392-17-7 | Adrenergic beta-1 Receptor Antagonists
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Description: Selective β1 antagonist

Chemical Name: 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemitartrate

Purity: ≥99%

Product Details
Supplemental Products

Biological Activity

Metoprolol tartrate is a selective β1-adrenoceptor antagonist (Ki values are 47, 2960 and 10100 nM for β1, β2 and β3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Beta-blockers reduce the release and synthesis of endothelin-1 in human endothelial cells.
    Garlichs et al.
    Eur.J.Clin.Invest., 1999;29:12
  2. S-metoprolol: The 2008 Clinical Review.
    Dasbiswas et al.
    J.Indian.Med.Assoc., 2008;106:259

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