Metoprolol tartrate

Key Product Details

Product Description

Metoprolol tartrate is a selective β₁-adrenoceptor antagonist (K_i values are 47, 2960 and 10100 nM for β₁, β₂ and β₃ adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo.

Product Specifications for Metoprolol tartrate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Metoprolol tartrate

The following data is based on the product molecular weight 342.40.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.92 mL	14.60 mL	29.21 mL
5 mM	0.58 mL	2.92 mL	5.84 mL
10 mM	0.29 mL	1.46 mL	2.92 mL
50 mM	0.06 mL	0.29 mL	0.58 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

• Dasbiswas S-metoprolol: The 2008 Clinical Review. J.Indian.Med.Assoc. 2008 PMID: 18828349
• Hoffmann Comparative pharmacology of human β-adrenergic receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmied.Arch.Pharmacol. 2004 PMID: 14730417
• Garlichs Beta-blockers reduce the release and synthesis of endothelin-1 in human endothelial cells. Eur.J.Clin.Invest. 1999 PMID: 10092983

Product Documents for Metoprolol tartrate