Potent and selective PI 4-K IIIβ
= 54 nM). Exhibits >1,800-fold selectivity for PI 4-K IIIβ
over PI 4-K IIIα
and PI 4-K IIα
, respectively. Exhibits antiviral activity against single-stranded positive sense RNA viruses in HeLa cell-based assays.
Soluble to 20 mM in DMSO
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Highly selective phosphatidylinositol 4-kinase IIIβ inhibitors and structural insight into their mode of action.
Mejdrová et al.