MI 14

Key Product Details

Product Description

MI 14 is a potent and selective PI 4-K IIIβ inhibitor (IC₅₀ = 54 nM). Exhibits >1,800-fold selectivity for PI 4-K IIIβ over PI 4-K IIIα and PI 4-K IIα, respectively. Exhibits antiviral activity against single-stranded positive sense RNA viruses in HeLa cell-based assays.

Product Specifications for MI 14

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for MI 14

The following data is based on the product molecular weight 450.94.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	11.09 mL	55.44 mL	110.88 mL
1 mM	2.22 mL	11.09 mL	22.18 mL
2 mM	1.11 mL	5.54 mL	11.09 mL
10 mM	0.22 mL	1.11 mL	2.22 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Mejdrová Highly selective phosphatidylinositol 4-kinase IIIβ inhibitors and structural insight into their mode of action. J.Med.Chem. 2015 PMID: 25897704

Product Documents for MI 14