Mind Bomb 1/MIB1 Antibody (S06-3D9)

Novus Biologicals | Catalog # NBP3-14955

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S06-3D9 expressed in HEK293
View all Mind Bomb 1/MIB1 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human Mind Bomb 1/MIB1 (Uniprot#: Q86YT6)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

110 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Mind Bomb 1/MIB1 Antibody (S06-3D9)

Western Blot: Mind Bomb 1/MIB1 Antibody (S06-3D9) [NBP3-14955]

Western Blot: Mind Bomb 1/MIB1 Antibody (S06-3D9) [NBP3-14955]

Western Blot: Mind Bomb 1/MIB1 Antibody (S06-3D9) [NBP3-14955] - Western blot detection of Mind Bomb 1/MIB1 in K562, Hela cell lysates using Mind Bomb 1/MIB1/Mindbomb Rabbit mAb (1:1000 diluted). Predicted band size: 110kDa. Observed band size: 110kDa.

Applications for Mind Bomb 1/MIB1 Antibody (S06-3D9)

Application
Recommended Usage

Western Blot

1/1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Mind Bomb 1/MIB1

E3 ubiquitin ligase protein mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. It positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.

Long Name

Mindbomb Homolog 1

Alternate Names

DIP1, MIB1, ZZANK2

Gene Symbol

MIB1

Additional Mind Bomb 1/MIB1 Products

Product Documents for Mind Bomb 1/MIB1 Antibody (S06-3D9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Mind Bomb 1/MIB1 Antibody (S06-3D9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

No product specific FAQs exist for this product.

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Associated Pathways

Notch Signaling Pathways Notch Signaling Pathway Thumbnail