(-)-JQ1

Tocris Bioscience | Catalog # 5603

Negative control for (+)-JQ1
Tocris Bioscience

Key Product Details

Description

Negative control for (+)-JQ1
View all Bromodomain Inhibitors »

Product Description

(-)-JQ1 is an inactive control for (+)-JQ1. Exhibits no significant interaction with BRD1-4 or a panel of other bromodomains.

Active Enantiomer also available.

Licensing Information

This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the (+)-JQ1 probe summary on the SGC website.

Product Specifications for (-)-JQ1

Molecular Weight

456.99

Formula

C23H25ClN4O2S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(6R)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester

CAS Number

1268524-71-5

PubChem ID

49871818

InChI Key

DNVXATUJJDPFDM-QGZVFWFLSA-N

SMILES

O=C(OC(C)(C)C)C[C@H]1N=C(C4=CC=C(Cl)C=C4)C3=C(SC(C)=C3C)N2C1=NN=C2C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 45.7 100
Ethanol 45.7 100

Preparing Stock Solutions for (-)-JQ1

The following data is based on the product molecular weight 456.99.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.19 mL 10.94 mL 21.88 mL
5 mM 0.44 mL 2.19 mL 4.38 mL
10 mM 0.22 mL 1.09 mL 2.19 mL
50 mM 0.04 mL 0.22 mL 0.44 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 72 publications citing the usage of this product.

Product Documents for (-)-JQ1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (-)-JQ1

For research use only

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