Mirin

Catalog # Availability Size / Price Qty
3190/10
3190/50
Mirin | CAS No. 1198097-97-0 | Checkpoint Control Kinase Inhibitors
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Description: MRN-ATM pathway inhibitor

Chemical Name: Z-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one

Purity: ≥99%

Product Details
Citations (5)
Reviews

Biological Activity

Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor that blocks the 3' and 5' exonuclease activity associated with Mre11. Prevents ATM activation in response to double strand breaks (IC50 = 12 μM) and induces G2 cell cycle arrest. Also blocks homology-directed repair in vitro.

Technical Data

M.Wt:
220.25
Formula:
C10H8N2O2S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
1198097-97-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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